The utility of thromboelastography in the monitoring of aspirin therapy

Abstract

To assess the utility of the Thromboelastogram in monitoring of aspirin therapy 25 healthy volunteers were selected and given low-dose aspirin therapy. Thromboelastography and platelet aggregometry were conducted at baseline and 1 week later. After 1 week of aspirin therapy, TEG data failed to demonstrate a significant change in the clotting profile. Platelet aggregometry identified significant changes in the clotting profile in response to stimulation with arachodonic acid, adrenaline and ADP
We conclude that thromboelastography may not have utility in monitoring of response to aspirin