Acquired bleeding disorders

N Alli; J Vaughan; S Louw; S Moodly; M Patel

doi:10.7196/SAMJ.2018.v108i3.13158

Continuing Medical Education

Acquired bleeding disorders

N Alli, J Vaughan, S Louw, S Moodly, M Patel

Abstract

Bleeding disorders are divided into two broad categories, i.e. inherited, discussed in part 1 of this CME series, and acquired, which is the subject of discussion in the current issue. In contrast to inherited haemorrhagic disorders, where generally a single haemostatic abnormality is found, multiple haemostatic defects are commonly present in acquired haemorrhagic diseases. Bleeding is often a presenting manifestation of systemic disease and requires a multidisciplinary team approach. Iatrogenic causes of abnormal haemostasis are of particular importance to the emergency physician. This CME article aims to provide an approach to the diagnosis and management of acquired bleeding disorders encountered in general practice.

Authors' affiliations

N Alli, Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, and National Health Laboratory Service, Johannesburg, South Africa

J Vaughan, Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, and National Health Laboratory Service, Johannesburg, South Africa

S Louw, Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, and National Health Laboratory Service, Johannesburg, South Africa

S Moodly, Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, and National Health Laboratory Service, Johannesburg, South Africa

M Patel, Department of Clinical Haematology, Division of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Johannesburg, and School of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa